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Fig. 2 Partial metabolic pathways of naphthalene in mammalians.
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Analysis of the reaction pathways responsible for formation of naphthalene, a typical representative of small PAH, was performed in order to elucidate the chemical effect of MP addition on its formation.
We then put together this sequence of metabolites into a pathway for naphthalene degradation (Zhang et al. 2000; Zhang and Young 1997).
This strategy enabled PP1Y to expand the pathway for the degradation of naphthalene and methylnaphthalenes, and to degrade larger PAHs.
From the metabolic pathway of S. koreensis, it could be concluded that this strain utilized 100 mg/L of naphthalene (two rings), phenanthrene (three rings), and pyrene (four rings) via two main pathways.
Changes observed in intermediary metabolism described effects in several pathways of liver energy metabolism due to naphthalene.
In previous studies, the genes involved in the degradation of naphthalene and o-xylene were identified, and the related metabolic pathways were characterized (Di Gennaro et al., [2010]).
Metabolism of naphthalene occurs in the liver by a single metabolic pathway following first-order kinetics.
GC/MS analysis of intermediate metabolites of LMW and HMW-PAHs concluded that this strain utilized 100 mg/L of naphthalene (two rings), phenanthrene (three rings), and pyrene (four rings) via two main pathways and phthalate was the major constant product that appeared in each day of degradation period.
During degradation of naphthalene and phenanthrene, the presence of cinnamate, salicylate, and phthalate indicates that this strain has two major pathways for naphthalene degradation.
A faint scent of naphthalene — the chemical used in mothballs — permeates the still air.
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