Numerous studies have been published that attempt to identify or reconstruct particular pathways of interest.
Consequently there are two pathways of interest related to NF-κB activation: Canonical and alternate.
Thus identification of candidate sets of GOI could help study the impact of treatments on specific pathways of interest in a given cell type.
If possible, limit unmeasured confounding in design phase of a study by considering mediational pathways of interest and collecting data on both X-Y AND M-Y confounders.
The human brainstem is a complex structure with several small nuclei and neural pathways of interest in the pathophysiology of central nervous system (CNS) disorders.
This approach requires that PET imaging be sensitive and specific enough to image various biological pathways of interest, e.g. tumor metabolism, proliferation and hypoxia.
Bulk RNA-SEQ was performed to further explore underlying mechanisms, revealing several potential pathways of interest including: RNA localization, splicing, ATPase regulation, IGF/PI3K/mTOR/AKT signaling, myriad of growth factor signaling pathways.
Genes that were unique to each affected twin were used to generate canonical pathways of interest.
The key theoretical pathways of interest here are how substance use and arrest influence each other over time.
Additional genes involved in the pathways of interest were included in the analyses.
These were only considered if they were involved in the pathways of interest.
