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Antagonism of VEGF, therefore, may have multiple pathways of interaction with other therapies, as well as direct antitumour effects.
It builds on the research already published and adds the dimension of a specific and highly prevalent chronic disease, dental decay, particularly dental decay that has progressed into the pulp and highlights pathways of interaction with all of the established factors contributing to poor child development.
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Correlating feedback from different HTS assays, can improve our understanding about pathways of interactions.
The possible pathways of interactions are direct strike, side flash, touch voltage, step voltage, subsequent stroke, connecting leaders and shock waves.
Shared common activities between these assays can enhance our understanding of the pathways of interactions especially when it is difficult to infer an explicit relationship between the biological targets (e.g. lacking protein protein interaction or lacking sequence similarity).
Our results provided some initial indications that StRab might play roles via regulating the secretary pathway of interaction proteins.
In addition, we speculate that there might be a pathway of interaction between photoperiod and temperature signals in rice.
As it is known, one of the widely used models describing the thermodynamics and kinetic pathway of interactions taking place between individual molecules makes use of the transient complex formation during a chemical transformation (or molecular interaction, for that matter) and is being placed at the core of the classical transition-state theory [50].
Activation of NF-κB and its associated pathway of interactions is controlled by inhibitors of NF-κB (IκB) proteins, which sequester the majority of NF-κB in the cytoplasm as complexes by masking their nuclear localisation signals [9].
By overlapping these data to the interactome, it is possible to identify a hypothetical pathway of interactions among protein domains, coupling it to their propensity to perform anti- or pro-apoptotic functions.
There are two different pathways of olation interaction between these complexes.
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