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To minimize errors in estimating personal exposures, researchers identify key sources, media, routes, and pathways of concern for each environmental pollutant and then determine an optimum sampling and analysis plan.
In this study, we estimated cumulative daily dose and health risk to determine the exposure pathways and conditions resulting in increased likelihood for dental fluorosis in children, with the vision that such information would be beneficial in identifying exposure pathways of concern and in managing risks for fluorosis.
In site A, where CCG leaders had access to comparative data from across the health system, the board leaders drew on existing strong relationships with the PCT to develop a solution in the form of joint working groups within the specialist areas and pathways of concern.
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At all locations, the primary exposure pathway of concern for elemental mercury is inhalation.
Dermal absorption of dichloromethane has been demonstrated in animals (McDougal et al. 1986) and in humans (Stewart and Dodd 1964), making this pathway another potential exposure pathway of concern, particularly in occupational settings without adequate protective gear and with improper use of consumer products (e.g., paint strippers).
However, precursor effects that are part of the toxic pathway are of concern.
Finally, a representation of the ToxCast and EDSP assays is shown to showcase which toxicity pathways might be of concern.
Table 1 lists the study areas, types of facilities, potential exposure pathways, and contaminants of concern.
The present analysis does not clearly identify indicators of exposure to waterborne or zoonotic pathways as exposures of concern in the participating communities.
High-throughput toxicology has defined adverse outcome pathways (AOPs), prioritized chemicals of concern, and identified novel actions of environmental chemicals.
Objectives: Our aim was to undertake an interdisciplinary geological- and health-science assessment to clarify lead sources and exposure pathways, identify additional toxicants of concern and populations at risk, and examine potential for similar lead poisoning globally.
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CEO of Professional Science Editing for Scientists @ prosciediting.com