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All that data provide major body of evidence, that the caspase cascade influences the regeneration of injured muscle and that one of the potential pathways of actions could be the modulation of IAP expression.
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Further, by identifying susceptibility genes and their pathways of action, it may be possible to identify previously unsuspected carcinogens.
The objective of this paper is to characterize CHW attributes and pathways of action using adapted measures, develop a scale using these measures, and explore how findings can inform future CHW research and practice.
To our knowledge, our study is one of the first to differentiate two pathways of action for visfatin-induced anorexia, hypothermia, and hypoactivity.
Delineating the pathways of action of these molecules in older people is therefore important.
Further studies are required to fully elucidate the pathways of action.
Future studies will focus on a more complete understanding of vorinostat's mechanisms and pathways of action.
Although the underlying mechanisms for the association are not yet definite many possible pathways of action have been reported.
We opted to use PubChem BioActivity to assess chemical similarity, assuming this measure of phenotypic similarity would be representative of underlying biological pathways of action.
Although the comprehensive list of biomarkers allowed us to investigate pathways of action at different stages along the ischemic cascade, it may raise concerns about multiple comparisons.
Together with our gene expression results, this confirms that mating and CO2-narcosis, despite producing the same final result, follow apparently different pathways of action.
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