Sentence examples for pathways needed for from inspiring English sources

The discovery of key signaling pathways needed for myeloma cell growth and proliferation has resulted in a plethora of new and different treatment options.

Thus INS-1 cells contain the synthetic pathways needed for processing of the NPY prohormone.

The coexpression analysis suggests IQD10 is likely involved in signaling pathways needed for secondary cell wall formation.

Essentially all pathways needed for cellular growth and proliferation are affected, and many of these have been targeted for drug research and development [ 2, 4].

These observations do not rule out different roles, however, including activation or repression of the different developmental pathways needed for posterior body development.

Erlotinib represents a new-generation of agents known as "targeted therapies" designed to act upon cancer cells by interfering with aberrant specific activated pathways needed for tumor growth, angiogenesis and cell survival.

An intriguing possibility is that the enzymes in the ubiquitylation pathway needed for p53 degradation are somehow inactive at that stage.

In C. elegans, DR has been associated with sensitivity to ROS stressors ([87] and Fig. S4), low glucose levels have been shown to promote ROS formation in [78], and LKB1/PAR-4 has been shown to be the upstream kinase of AAK-2 in a pathway needed for oxidative stress resistance [68], implicating ROS in pathways relevant to the metformin model.

JAK/STAT is now recognized as a critical pathway needed for efficient muscle fibre adaptation.

Autophagy is also a major pathway needed for the clearance of pathogens in immunity and helps in maintaining cellular homeostasis.

The latter inhibitors are relevant to virulence because we previously showed that they inhibit the secretory pathway needed for capsule formation [ 32].