Sentence examples for pathways may modulate from inspiring English sources

Additionally, intracellular signaling pathways may modulate ROS production as discussed above, opening the possibility for future therapeutic interventions.

Accumulating evidence shows that crosstalk of TNF-α and IGF-1 signaling pathways may modulate biologic functions in cardiovascular tissue.

More detailed information on how inflammatory pathways may modulate ventricular electrophysiology is required and represents an area of some interest.

Finally, we discuss how cytoplasmatic signaling pathways may modulate the function of ER and its cooperating transcription factors.

Clearly, our model is at present simplistic, as it describes a direct causality between EGFR activation, Erk status and proliferation, when in reality, cross-talk from other signalling pathways may modulate at all levels.

In this review, we describe how cooperating factors influence the transcriptional activity of ER, and we speculate how these signaling pathways may modulate the function of ER and ER-cooperating factors.

Wnt/β-catenin signaling recently has been shown to promote inflammation and apoptosis, suggesting that activation of this signaling pathway may modulate ALD progression.

Gene expression analysis before and after PH show that UPF2 null mice induce a transcriptional program that overlap only partially with the one induced in WT mice and suggest that the NMD pathway may modulate central components required for regeneration.

Hence, manipulation of this pathway may modulate chemotoxicity in cancer cells.

The above data suggest that β-oxidation may be important to support the lifespan; alterations in the activity of this pathway may modulate CLS of peroxisome-deficient cells.

Similarly, the Ire-1/Traf2 pathway may modulate the JNK response genes that are up regulated in loj mutants (see Additional files 2, 3 and 5).