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GSEA and PPI network analysis also suggested that the p53 and WNT pathways may be dysregulated.
These alternative pathways may be derived from a spatial specialization of BR functions within the root.
Therefore, targeting aberrantly activated STAT5 or rewired downstream signaling pathways may be a promising therapeutic option.
This mutual exclusivity suggests that both pathways may be functionally redundant and complement each other in colorectal carcinomas.
Important low abundance TFs, signaling molecules and associated bioprocesses and pathways may be lost in scRNA-seq studies.
Recent studies indicated that the auxin and cytokinin (CK) signaling pathways may be involved in defence response31.
Molecules and genes in those pathways may be potential targets to develop treatments for ovarian cancer.
Furthermore, protein-protein interactions and activation of signal transduction pathways may be visualized noninvasively.
Testing the aggregation of genetic variants, in particular biological pathways, may be more powerful.
The fibroblast growth factor receptor (FGFR) signaling pathways may be a relevant target in MPM.
In both situations, same molecular pathways may be involved to different degrees.
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