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The Ingenuity Pathways Knowledge Base is currently the world's largest database of knowledge on biological networks.
Agilent probe identifiers were mapped to their corresponding gene objects in the Ingenuity Pathways Knowledge Base.
Each gene identifier was mapped to its corresponding object in the Ingenuity Pathways Knowledge Base.
These genes were then used to generate biological networks developed form information contained in the Ingenuity Pathways Knowledge Base (IPKB).
Each uploaded gene identifier was mapped to its corresponding gene object (focus genes) in the Ingenuity Pathways Knowledge Base.
This software assigns biological functions to genes using the Ingenuity Pathways Knowledge Base (Ingenuity Systems, Inc., Redwood City, CA).
A data set containing protein identifiers and corresponding expression values was uploaded into in the application Ingenuity Pathways Knowledge Base.
Of 1663 gene identifiers, 1660 were successfully mapped to its corresponding gene objects in the Ingenuity Pathways Knowledge Base and 1303 were identified as network eligible.
This knowledge coming from published, peer-reviewed scientific publications is stored in the Ingenuity Pathways Knowledge Base (IPKB), and is continuously updated.
Relationships were examined manually in the Ingenuity Pathways Knowledge Base to determine if target genes were activated or repressed by p53.
These genes, or focus molecules, were overlaid onto a global molecular network developed from information contained in the Ingenuity Pathways Knowledge Base.
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