Sentence examples for pathways is achieved from inspiring English sources
Evolutionary diversification of NRPS and PKS pathways is achieved through genetic mechanisms such as recombination, duplication, fusion or fission of genes, deletion or substitutions of domains, circular permutations, gene loss and horizontal gene transfer [ 32, 33].
However, direct integration over signals from cAMP and cGMP pathways is achieved via the integrator protein VASP and its phosphorylation sites, thereby also monitoring the effects of anti-platelet drugs.
Such segregation of the pathways is achieved by the lack of disulfide exchange between DsbA and DsbC and the inability of DsbB and DsbD to oxidize or reduce DsbC or DsbA respectively [ 35].
The activation and de-activation of genes participating in signaling pathways is achieved by several mechanisms, including the binding of transcription factors (TFs) to cis-elements in the promoter region of affected genes, which thereby become activated or suppressed.
In LL016, two CO2 fixation pathways were achieved and NAD+ supply was enhanced by co-expression of heterologous pyruvate carboxylase (PYC) and nicotinic acid phosphoribosyltransferase (NAPRTase).
Reconstruction of the pathways was achieved according to the method described by Krings et al. [ 17].
Synergistic therapeutic effect and regulation in tumor pathways are achieved by combining the drug with orthogonal therapeutic moieties like siRNA.
The P-values for over-represented (enriched) and under-represented pathways were achieved using the GoSeq default method "Wallenius" by the Wallenius non-central hypergeometric distribution [ 60].
Inhibition of fibroblast mammalian target of rapamycin (mTOR), Akt, and glycogen synthase kinase 3β (GSK-3β) signaling pathways was achieved using small-molecule pharmacologic inhibitors.
New insight into the regulation of essential developmental, inflammatory and apoptotic pathways was achieved with the discovery and characterization of the NLR gene family of putative cytoplasmic pattern recognition molecules.
How timely activation of the degradation pathway is achieved is still incompletely understood.
