Sentence examples for pathways in small from inspiring English sources

In addition, that we identified ten pathways common to at least five of the melanoma samples confirms the idea that protein network-guided analysis is a good method for detecting recurrently affected pathways in small datasets.

Pathway ranking has been shown to extract biologically meaningful pathways in small metabolic sub-networks (Takigawa and Mamitsuka, 2008).

This approach allowed us to confirm or reconsider known disruptions in signaling pathways in small intestinal NETs and identify pathways involved in development as well as novel transcription targets with putative therapeutic and biomarker potential.

Regional availability of p53-dependent and -independent apoptotic pathways in small and large intestine together with separate modulation of these pathways by antioxidants explains the different regional enterotoxicity following 5-FU therapy.

Another emerging proteomic technology is the SOMAscan proteomics platform, which can efficiently, accurately, and rapidly identify and quantify over 1000 proteins across a wide range of concentrations (while targeted analysis is more suitable for examining specific metabolic pathways) in small sample volumes [71].

However, more expensive, large animal (canine, porcine, primate) MI models are needed to confirm results of small animal experiments before clinical testing, since the temporal and spatial development of MI as well as certain signalling pathways in small animals differ from that in larger mammals and humans [ 21, 53, 55 ].

It varies the tortuous polymeric diffusion pathways in smaller particles [21].

If Calindol's action on the [Ca2+]o-modulated NSCC signaling pathway in small nerve terminals was mediated via CaSR we reasoned that this latency should also be present in measurements using heterologously expressed CaSR.

The biochemical and signaling pathways in the small intestine that were affected by fasting were identified using P < 0.01 and ≥ 1.4-fold change as thresholds for individual genes.

Among them, 11 pathways are shared by the preserved and dysregulated miRNAs, which include pathways in cancer, small cell lung cancer, p53 signaling pathway, focal adhesion, cell cycle, bladder cancer, glioma, colorectal cancer, prostate cancer, pancreatic cancer, and melanoma.

We determined the availability of p53-dependent and -independent apoptotic pathways in the small and large intestine following 5-FU therapy and characterised the effect of PDTC upon each pathway.