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The exact pathways implicated in these processes need further investigation.
Alternate pathways implicated in tumor growth also exhibited upregulation such as VEGF signaling with 49 molecules.
Better understanding of post-translational modifications will allow more comprehensive mapping of networks and pathways implicated in certain diseases.
Nintedanib is an oral angiokinase inhibitor targeting multiple signaling pathways implicated in the pathogenesis of MPM, including the VEGF receptor.
The signal transduction pathways implicated in this process are evaluated as potential targets for therapeutic intervention and drug design.
Other polymorphisms in dopamine or serotonine receptors might be involved as these neurotransmitters control OF thalamo-striatal pathways implicated in impulse control.
Comparing in vivo imaging in animals with genetic alteration of pathways implicated in angiogenesis allows exploration of downstream effects in live animals.
Gefitinib is an orally active epidermal growth factor receptor tyrosine kinase inhibitor that blocks signal-transduction pathways implicated in the proliferation and survival of cancer cells.
The frameworks are demonstrated on a large-scale reconstruction of a signaling network composed of nine signaling pathways implicated in prostate cancer.
Our candidate genes act in pathways implicated in aging and longevity, including neurodegeneration, cognitive function, lipid metabolism, DNA repair, and genome maintenance.
The host response was evaluated by measuring 23 biomarkers providing insight into key pathways implicated in sepsis pathogenesis and by analyzing whole-blood leukocyte transcriptomes in samples obtained within 24 h after ICU admission.
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