The phytosterol and linolenic acid pathways had low SNP abundance, and therefore low variation (data not shown).
Mutations of the Ras and β-catenin pathways had low p-values in the EPSA and Bild analyses, but neither were significant when corrected for multiple hypothesis testing.
Previous research on Chlamydomonas reinhardtii reported that the gene cluster associated with lipid metabolism had high expression during the lipid accumulation phase, and the gene cluster associated with photosynthesis and basic metabolic pathways had low expression during the stationary phase [ 34].
These results indicate that 1) connection weight heterogeneity plays an important role in determining cortical network specificity, 2) high investment in local projections highlights the importance of local processing, and 3) transmission of information across multiple hierarchy levels mainly involves pathways having low FLN values.
Most metabolites of the dopamine pathway have low concentrations in the human brain, so that even small amounts of medication would evoke relatively large deviations and could thereby be quite efficacious.
When a pathway has low completeness or lacks sufficient annotations, the predictions would have large deviations.
Twenty-one genes in the sialylated oligosaccharide metabolism pathway had low to medium levels of expression in Holstein and Jersey milk (Figures 3 and 4).
For instance, the M pathway has low spatial resolution, detects low contrast and motion, is color-blind, and has a fast response (7,8).
In agreement, the sample 39 harboring the EGFR stop codon mutation and, presumably, associated with an inactive pathway, had low PTEN expression (9% or score 0).
A pathway had "Low" taxonomic disagreement if in the upper two quartiles of negative distances (i.e., those closest to zero), "Medium" if in the second quartile, and "High" if in the bottom (i.e., most negative) quartile.
