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To further investigate the two pathways for H3 + formation under identical conditions, an organic molecule capable of reacting via both pathways has to be studied.
In general, our results suggest that, in order to identify potential biomarkers and drug targets for prion diseases and other neurodegenerative disorders, a combination of various pathways has to be targeted, including oxygen homeostasis, lipid metabolism and inflammation response.
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To gain access to this potential reservoir of bioactive compounds, the cryptic biosynthetic pathways have to be induced.
All metabolic pathways have to be regulated and controlled to stop the build-up of an end product that isn't needed.
Originally, the pathways had to be opened within 21 years after being designated for public use, and dozens were in danger of expiring in 2002.
Indeed, two parallel pathways have to be assumed.
The question therefore arises if all adjacent metabolic pathways have to be considered in the kinetic model.
Mechanisms by which topoisomerase-targeting drugs induce I κB degradation to activate the NF- κB pathway have to be elucidated.
It should be noted that interaction between AR and Akt/mTOR pathways has been reported to be involved in tumorigenesis.
Aberrant activation of RTK pathways has been shown to be involved in the development of various types of cancers [3] [6].
Indeed proteins belonging to these pathways have been reported to be essential in other organisms as well [ 10, 65, 66].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com