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The Arabidopsis secondary metabolite pathways further support the relationship between pathway transcript CV and biological function.
Additional actions on conserved cell signaling pathways further support explorations into the use of US as a neuromodulation tool.
The EGFR and JAK-STAT pathways further regulate the pattern of follicle-cell differentiation along the anterior-posterior (AP) axis of the egg chamber.
Therefore, for the demanding tasks of assembling and cloning complex synthetic gene libraries and pathways, further improvements on accuracy and efficiency over existing methods would be highly desirable.
In addition, the current annotation of the pig genome has limited availability of GO terms and KEGG pathways further reducing the sensitivity of the analysis.
The fact that both Zfp277 and PcGs are crucial for repression of the Ink4a/Arf locus and inversely regulated downstream of stress pathways further supports that functional crosstalk occurs between Zfp277 and PcGs.
The dynamical behavior of signal pathways is highly complicated; many ligands, homologous genes, alternative splice variants and regulatory factors are involved in the signaling, and different pathways further interact or cross-talk with one others, all together impacting the dynamic response to ESC differentiation or self-renewal.
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In addition, PKM2 itself indirectly activates the pentose phosphate pathway, further facilitating the NADPH production [15].
However, genetic engineering of the sphingolipid pathway further increased secretion of TAPS.
Combining the synthetic Entner Doudoroff pathway with an optimized terpenoid pathway further increased the terpenoid titer by 97%.
Co-existing mutations in PI3K/AKT pathway further confers resistance to MEK inhibitor treatment in KRAS mutant CRC (Shimizu et al., 2012).
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