Sentence examples for pathways for therapy from inspiring English sources

Lastly, we present a provocative view of the clinical relevance, emerging challenges in dual targeting of redox and autophagy pathways for therapy, and the future directions to be addressed in order to advance both basic and translational aspects of this field.

We provided additional support for the metabolic symbiont model and discovered that breast cells prevailingly take up and catabolize lactate, providing rationale for future studies on manipulation of lactate catabolism pathways for therapy.

Thus, our data invoke caution when interfering with B7 co-stimulatory pathways for therapies, a concept largely debated in the literature [51], [52].

A.L.D., A.T.P., R.S.J. and A.W.G. hold a provisional patent for manipulation of the VHL-HIF pathway for therapy.

We propose that PGE2 plays a role as a negative regulator of MIP-1α production in the pathogenesis of SD, and that PGE2-EP2 and 4/cAMP/PKA signaling could be a target pathway for therapy for SD.

Therefore, attempts to target the MEK-ERK pathway for therapy of breast cancer might not be successful in such cases (Shen and Brown, 2003).

Manic, G., Obrist, F., Sistigu, A. & Vitale, I. Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy.

This study established a novel tumor-suppressor role of miR-101 in cholangiocarcinoma and it suggests the possibility of targeting miR-101 and related signaling pathways for future therapy.

One of the promising candidate pathways for targeted therapy in DLBCL is the STAT3 pathway [ 13].

These signaling pathways are well studied, and several drugs have been developed to target different pathways for cancer therapy.

PI3K/AKT/mTOR and RAS/RAF/MEK/ERK pathways are thought to be the central transducers of oncogenic signals in solid malignancies, and there has been a lot of enthusiasm for developing inhibitors of these pathways for cancer therapy.