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Lipid rafts are plasma membrane platforms mediating signal transduction pathways for cellular proliferation, differentiation and apoptosis.
Endocytosis is one of the primary pathways for cellular uptake of nanoparticles [38].
These channels serve as pathways for cellular communication that coordinate diverse physiologic processes.
Drugs can also induce mutations of the targets and inhibit pathways for cellular apoptosis, leading to resistance.
Cancer is a complex family of diseases, characterized by the deregulation of normal control pathways for cellular growth.
The relative importance of each of these pathways for cellular senescence seems to depend on the cell type.
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Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA et al. Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Besides, an endocytic and a passive diffusion pathway for multi- and single-walled CNTs transmembrane process [27, 28], and an oxidative stress pathway for cellular apoptosis induced by carbon nanoparticles, were proposed [39, 40].
Intriguingly, four ruminant Tetherins do not contain the YxY motif, suggesting that these Tetherins may have another pathway for cellular trafficking.
This recombinant toxin uses precisely the same PA-dependent pathway for cellular entry as that used by wild-type LF, and indeed it has been used as a convenient tool to study the anthrax toxin entry mechanism because, unlike wild-type LF, it can cause cell death in many cell types following its translocation into the cytosol [19] [21].
Proteasomal degradation is the main pathway for cellular degradation of proteins.
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