Exact(2)
While individual drugs may affect a set of regulatory genes or pathways, combining drug actions in the context of biological mechanisms underlying the disease condition could lead to more effective therapies for a complicated clinical situation.
For example, if some other resource is able to link proteins to pathways, combining it with our pipeline (that can link mutations to proteins) would make it possible to find a pathway in which a mutated protein participates.
Similar(58)
Together these pathways combine to support perception.
The pathways combine two main dimensions: degrees of harmonisation and instruments and design elements.
It is assumed that these pathways combined with oxidative phosphorylation have reached, during their evolution, a high efficiency with respect to ATP production rates.
The experiential course, entitled Healing Pathways, combined training in Reiki, guided imagery, yoga, toning, meditation, intuitive scanning, creative expression, and mentorship to foster more empowered and resilient individuals.
Other advantages are the possibility of studying regional differences in intestinal absorption and the assessment of drug transport pathways combined with drug metabolism.
These signaling pathways combined with the classical signaling pathway, with ERK1/2 as a hub node molecule, form a molecular signaling cross-talking network to induce the osteogenic differentiation of hMSCs.
The hypothesis that TMD pain is caused by a generalized sensitization of higher order neurons in the nociceptive pathways combined with a decreased efficacy of endogenous inhibitory systems has recently gained support in the literature.
Advances made in recent years that 'humanize' plant glycosylation pathways combined with the discovery of terminal sialic acids (SAs) in plants now make feasible the bioengineering in plants of glycoproteins that have mammalian-like glycosylation.
An integrated, systems meta-analysis of the over-represented pathways combined the expression and GWAS results using a Fisher's combined probability test.
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