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We then used in vivo pharmacological manipulations to establish that augmented LMAN activity is sufficient to restore high levels of sequence variability in adult birds, suggesting that recurrent interactions through highly distributed forebrain-midbrain pathways can modulate learned vocal sequences.
Recent years have made clear that interference with podocyte-specific disease pathways can modulate glomerular function and influence severity and progression of glomerular disease.
Crosstalk between the canonical and non-canonical pathways can modulate chondrocyte differentiation and cartilage matrix synthesis.
It has been reported that adrenergic pathways can modulate gut motility [ 19].
It indicates that various signaling pathways can modulate serine phosphorylation of Mt STAT3 in tumor cells.
Furthermore, these pathways can modulate the effectiveness of chemotherapy in lung cancer patients [ 26].
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Consequently, inhibition of the NHEJ pathway can modulate a radiation- or chemo-refractory disease presentation.
The PI3K/Akt pathway can modulate functions of ABC transporters through various mechanisms.
Moreover, the Hippo pathway can modulate asymmetric cell division of NSCs (Keder et al., 2015) and regulate glial cell proliferation (Reddy and Irvine, 2011).
These observations suggest that the Rapl-Mst1 pathway can modulate cell proliferation and T-cell migration [7], [8].
Our study showed that the eNOS/PRC signalling pathway can modulate the cell cycle by regulating the intracellular redox status.
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