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Disruptions in these molecular pathways can cause disease.
Scientists believe that disturbances in these "biological pathways" can cause disease.
Dysfunctions in a number of cellular pathways can cause Parkinson's disease.
Deficiencies in these pathways can cause cells to accumulate genomic errors that lead to human diseases, including somatic cancers and Mendelian inherited genetic disorders.
If left unregulated, these inflammatory pathways can cause joint damage.
Reactive oxygen species (ROS) produced from various metabolic pathways can cause oxidative damage [ 42].
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Just as observed for catalytic activity, different variants of the same position in the putative PT pathway can cause significantly deviating shifts in pH optimum.
In humans, the Hedgehog pathway has long been known to contain genes that control fetal development and cell growth, and, when altered, the pathway can cause excessive cell growth, a hallmark of cancer.
Furthermore, alterations in the thyroid hormone pathway can cause short stature [53], [54].
Less severe perturbations to the insulin pathway can cause increased entry into the dauer stage or into the adult diapause.
An interesting consequence of independent pathway competition is that fairly small changes in kinetics of either pathway can cause large changes in average cell fate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com