The intracellular components of TCR signalling pathways can also be manipulated to optimise anti-tumour responses.
Fitter amino acid biosynthetic pathways can also be mechanisms that better explain biomass yield in cryotolerant strains.
Other alterations, both upstream and downstream of BRAF can have the same effect, and activation of alternative pathways can also play a role in resistance to BRAF inhibitors.
New pathways can also be constructed both in plasmids and on chromosomes for Halomonas spp. Synthetic biology approaches and parts have been developed for Halomonas spp., allowing better control of their growth and product formation as well as morphology adjustment.
Pathways can also be ranked based on path length (e.g., algorithms finding k-shortest paths [27, 42]).
The rampant crosstalk that occurs among mammalian signaling pathways can also mask the effect of small molecules.
Disappearance of fluorescence-tagged mitochondrial proteins is a supporting evidence for mitochondrial clearance; however, partial degradation of proteins without mitochondrial removal and mitochondrial clearance through alternative pathways can also result in elimination of fluorescence.
The network of inter-relationships among pathways can also be used to interpret the existing information and new predictions on potential resistance mechanisms to PI3K inhibition in PI3KCA mutant, ER+ breast cancer (Fig. 6b).
Motor pathways can also disintegrate and limit attention spans.
However, it has been shown that Bid-independent pathways can also lead to mitochondrial activation [6].
Network analysis of biological pathways can also be a useful tool to augment pathways with knowledge from various resources.
