Sentence examples for pathways can act from inspiring English sources

Although originally described as linear entities, increasing evidence suggests that many signaling pathways can act as both inputs and outputs within the overall network.

Thus, the PI(3 K-Akt and NFκB pathways can act independently of each other in an endogenous model of oxidative stress.

Genetic interaction studies of endocytosis or ubiquitination reveal that barrier pathways can act in linear, parallel, or feedforward loop architectures to antagonize reprogramming.

However, there are examples where the two pathways can act cooperatively to create a molecule [ 30].

Some of these pathways can act in concert to trigger EMT.

However, there are examples that two pathways can act cooperatively to create a molecule [ 16].

The flux of nutrients along each metabolic pathway is governed chiefly by two factors: (1) the availability of substrates on which pacemaker, or key, enzymes of the pathway can act and (2) the intracellular levels of specific metabolites that affect the reaction rates of pacemaker enzymes.

Together, our data demonstrate that a single signaling pathway can act reiteratively to coordinate organ size and proportion.

In advanced cancer, the TGF-β/SMAD pathway can act as an oncogenic factor driving tumor cell invasion and metastasis, and thus is considered to be a therapeutic target.

Their model includes both a deterministic and a stochastic description of the pathway and proves mathematically that the Notch signalling pathway can act both as a bistable switch and as an oscillator depending on the level of repression Hes1 homodimers apply on the N box sites (via a parameter termed rbox).

The data presented here demonstrate that the Drosophila sexual differentiation pathway can act during development and in adults to affect longevity.