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A major question in the field is whether PINK1-dependent pathways are linked to pathways mediated by other PD-linked genes.
In contrast, peripheral alpha- and beta-adrenoceptor-related signaling pathways are linked to up-regulating processes.
Although considerable data have demonstrated that suppression of the insulin/IGF-1 and mTOR signaling pathways are linked to lifespan extension, the underlying mechanisms remain elusive.
The behavioral overlap of co-morbid diagnoses is due to the widely distributed networks with which central auditory pathways are linked, in bottom-up, top-down, and reciprocal loop processes [5].
Several authors claim that the comorbid diagnoses of the impairment of auditory processing, and the disorder of attention, cognition, or language, are due to the widely distributed networks with which central auditory pathways are linked, in bottom-up, top-down, and reciprocal loop processes [9].
It is currently unknown if the two pathways are linked.
Similar(15)
In children with the version of the gene not linked to autism risk, the pathways were linked more strongly to the left side of the brain.
Aberrant signaling through Wnt signaling pathways is linked to a number of diseases including cancer [3] [6].
In addition, network analysis also revealed that different innate immune pathways were linked together by calcium-activated transcription factors.
However, only in a few cases have these pathways been linked to specific signaling outcomes.
The laboratory studies identified that the leptin signaling pathways were linked to the pathophysiology of AD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com