Sentence examples for pathways are fully from inspiring English sources
Because under such conditions the adaptable pro-aging pathways are fully suppressed and the adaptable anti-aging pathways are fully activated, a compound that can increase life span is expected to target the housekeeping longevity pathways.
Interestingly, rapamycin has been shown to increase life span in fruit flies under dietary restriction conditions [ 25], when the TOR-governed adaptable pro-aging pathways are fully suppressed and the TOR-governed adaptable anti-aging pathways are fully activated [ 3, 4].
This activation via glucorticoids signaling pathways was fully prevented by cyclotraxin-B, contrary to a functional anti-TrkB antibody capable of inhibiting BDNF-dependent TrkB activity only.
In addition, most of the amino acid pathways were fully or partially incomplete in Tfu_v2.
The results indicated that these pathways were fully represented (Table 4), and that most putative enzymatic activities were present with a significant degree of redundancy, both in terms of EST (expression) and Unigenes (putative paralogs) numbers.
Figure 1b lists all the Recon 2 pathways consisting of more than one reaction, ordered by their combined median activity in all analyzed cell types with the first pathways (from left to right) showing no activity in almost none of the analyzed cell types and the last pathways being fully active in almost all cell types.
These findings strongly support the hypothesis that mammalian cells can enter into next cell cycle until DSBs accumulate to a threshold level and senescence-related DNA damage signals p53-p211 pand/or and/oRb-p1616 pathway) are fully activated to arrest the cell cycle.
Even before the RNAi pathway was fully understood, it was known that induced gene silencing in plants could spread throughout the plant in a systemic effect and could be transferred from stock to scion plants via grafting.
Finally, the human NIR pathway was fully reconstituted in vitro using the purified APE1, human flap endonuclease 1, DNA polymerase β and DNA ligase I proteins, thus establishing the minimal set of proteins required for a functional NIR pathway in human cells.
As shown in Figure 2C, this pathway is fully functional in atg36Δ cells.
Thus, the core of the Nrf2 pathway is fully conserved and composed of non-redundant gene products in Drosophila.
