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TUNEL assay also showed the orthotopic TRAMP-C1 siAR tumours + CCR2atg had the highest number of apoptotic cells (Fig 6E), suggesting that both AR and CCL2 pathways are essential signals for PCa tumourigenesis.
The endosomal trafficking pathways are essential for many cellular activities.
DDR pathways are essential for sensing, processing and repairing DNA damage.
The three-dimensional thymic microenvironment and calcium signaling pathways are essential for driving positive selection of developing T cells.
Furthermore, our results also showed that AhR-Cyp1A1-Nrf2 pareways aressentialal for UroA/UAS03 mediated upregulation of tight junction proteins (Figs. 2 and 3).
Isnardi I, Ng YS, Srdanovic I, Motaghedi R, Rudchenko S, von Bernuth H, et al. IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans.
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The knowledge of biotransformation pathways is essential to the design of metabolically stable leads with acceptable pharmacokinetic characteristics.
Understanding the contribution to each of these intracellular pathways is essential for the elucidation of mechanisms that drive pathophysiology.
Reconstruction of highly efficient biosynthesis pathways is essential for the production of valuable plant secondary metabolites in recombinant microorganisms.
Understanding these diverse pathways is essential to the treatment of pancreatitis, diabetes and obesity.
After a trauma, use of a systematic approach to explore the main functional components of auditory pathways is essential.
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