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Moreover, these pathways are embedded within the global signaling network of the cells.
A major obstacle to this goal, however, is the challenge of understanding the design logic underlying the complicated, interconnected networks in which most signaling pathways are embedded.
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The alternative monitoring pathways were embedded in a Markov model simulating the occurrence of adverse events over time for a hypothetical cohort of people with AF or AHV (figure 1).
The redesign of the surgical pathway was embedded in the new strategies to improve the performance of the clinical system.
Second, the Kennedy pathway consists of 3 enzymes that convert the metabolite ethanolamine into PE; the last enzyme in this pathway is embedded in the membranes of the endoplasmic reticulum (ER) (Fig. 1 ).
A major feature of network-boosted analysis is to reduce data complexicity by highlighting individual pathways and possibly inter-connected pathways that are embedded into modules seeded with gene activity.
Such care pathways incorporate clinical guidelines in that the latter are embedded into the pathway itself.
In contrast, JEPETTO integrates gene sets with pathways and the molecular interaction networks they are embedded in.
The Fryback and Thornbury framework [ 10] recognises that medical tests are embedded in a clinical pathway.
Lastly, it is now apparent that processes like neurogenesis and neuroplasticity are embedded within layers of interlocked signaling pathways and gene regulatory networks.
Baccarat screens are embedded in a tabletop.
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