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The classical and alternative pathways are composed of different proteins in the first part of their cascades, but eventually both pathways converge to activate the same complement components, which destroy and eliminate invading pathogens.
This is a database of biological systems, consisting of the genetic building blocks of genes and proteins; the identified pathways are composed by molecular interactions and reaction networks for metabolism, various cellular processes, and human diseases.
First, corticostriatal pathways are composed of focal, circumscribed projections and of diffuse, widespread projections.
These pathways are composed of 777 enzymes that catalyse 1,211 enzymatic reactions.
The RNA transport pathways are composed of various protein complexes that regulate gene expression and nucleocytoplasmic trafficking.
The light signaling pathways are composed of phytochromes, transcription factors and numerous intermediates which control photomorphogenesis including chloroplast development.
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Furthermore, the dose-dependently down-regulated pathways were generally composed of general metabolism-related pathways, while the up-regulated pathways were composed of signaling or disease-related pathways.
Cancer related pathways were composed of 86 pathways related to cell cycle regulation, 9 pathways in apoptosis, and 7 pathways in cell growth (Additional file 6: Table S6).
Moreover, considering that KEGG pathways were composed of nodes which were actually modules including single gene or multiple functionally similar genes, we further analyzed the number and percentage of the nodes containing Class II genes in each of the enriched pathways.
Nodes in the pathway are composed of one or more proteins.
This pathway is composed of an acetolactate synthase, an acetolactate decarboxylase and an acetoin reductase.
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