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Many of these spiritual pathways are based somewhat loosely around Native American traditions, including the ceremonial sweat lodge.
All three of these pathways are based on the idea that loved ones share social norms, the implicit cultural beliefs that make some things okay, others not.
Given that BCL-2 is overexpressed in many tumors, most strategies to engage apoptosis pathways are based in the blockade of anti-apoptotic members of the BCL-2 family.
Canonical pathways are based on the literature (journal article, KEGG pathways) and are used to overlay expression changes.
Ingenuity Pathways are based on a constantly curated database of published literature on gene functions and interactions (https://analysis.ingenuity.com).com
The other pathways are based on indirect associations.
The main limitation of the study is that pathways are based on expert clinical opinion, rather than prospectively collected data.
These pathways are based on the existing literature and variables available in the main dataset used in the analysis.
Support for the gene connections in metabolic pathways are based on information from KEGG [ 50], and AraCyc [ 51] databases.
Numerous cellular signaling pathways are based on the sequential phosphorylation of an array of proteins [ 15, 33, 46].
Note that many studies on signaling pathways are based on experiments in vitro or with cell lines and may not reflect the scenario in vivo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com