Sentence examples for pathways and will from inspiring English sources
Down-regulation of Nanog and Sox2 gene expression can change multiple gene expression patterns and signal transduction pathways, and will initiate ES cell differentiation.
Metabolic pathfinding may not be the main focus of retrosynthesis algorithms and expanded databases; however, these resources are nevertheless critical for finding novel metabolic pathways and will be included in this review.
Broadly speaking, any mechanism that yields the restoration of activity in the PI3K, MAPK, AKT or mTORC1 pathways, or increased activity of the ER pathway, will restore the proliferation-inducing and/or apoptosis-opposing effects of these pathways, and will yield a decrease in the effectiveness of PI3K inhibitors.
A new paradigm regards apoptotic pathways as complex signaling mechanisms that interact with a wide range of cellular pathways and will not always trigger cell death, as has been the subject of a number of recent reviews [10], [55], [56].
The simple and robust procedure elaborated here to assemble multilayered biomimetic structures will be instrumental to reconstitute multimolecular complexes involving both cytosolic and membrane embedded proteins such as those implicated in many cell signaling pathways and will also be useful to characterize protein translocation across membranes.
The EC method is limited to only enriched pathways and will miss any non-enriched pathway.
A spokesperson for the Welsh government said it is committed to tackling obesity through the all Wales obesity pathway and will be considering the findings of the report.
It is not a part of the canonical Ras-MAPK pathway and will not be covered in this Review.
Our results will enhance the current understanding of RB-E2F pathway and will also be useful to further functional studies in human and other model organisms.
A predefined topic guide will be used to cover key aspects of the critical illness pathway and will include possible short- and long-term complications.
Lesions from groups 2 and 3 have a final common pathway and will both result in pseudarthrosis with the typical appearance of the AL (Fig. 1).
