Sentence examples for pathways and trigger from inspiring English sources

Interestingly, although UV-induced photoproducts and DSBs are processed by different DNA repair pathways and trigger signaling responses controlled by distinct apical kinases (see above) they eventually generate the same epigenetic mark involving H2A ubiquitination [59].

Despite these differences, both Type I and Type III IFN have similar mechanisms of induction, activate the same signaling pathways, and trigger the same biological actions in the target cell [ 11].

Oncolytic viruses carry great potential as broadly active cancer therapeutics, as they simultaneously interfere with multiple cell survival signaling pathways and trigger inflammatory responses, which, in turn, may expose the tumors to the immune system.

Oxidative stress activates inflammatory pathways and triggers a series of events that lead to organ injury [ 42].

Maps also identify constraints, pathways and triggers and can document change by comparing maps generated at different points in time or place.

Researchers have suggested that repeated alcohol use gradually enhances incentive salience and craving response toward alcoholic beverages by altering the reward pathways and triggering more alcohol craving and drug seeking (Breese et al. 2011; Robinson and Berridge 1993).

BPA activated both cAMP-dependent protein kinase and cGMP-dependent protein kinase pathways and triggered a rapid (15 min) phosphorylation of the transcription factor cAMP response-element binding presponse-element bindingll cycle regulator retinoblastoma protein (Rb).

We therefore propose that CT45A1 acts as a new proto-oncogene, which activates the expression of numerous oncogenic genes, activating several key signaling pathways, and triggering tumorigenesis and cancer metastasis in a favored environment.

61 Ligand engagement by AGE-binding receptors activates several critical molecular pathways and triggers a number of effects; these include pro-oxidant events via generation of reactive oxygen species and further proinflammatory events via NFκβ signaling.

The increased ROS generation reduces the antioxidant defense mechanisms of the outer hair cells, causing the release of cytochrome c from mitochondria, activating the caspase pathways, and triggering apoptotic cell death [ 51].

Moreover, we found that NAA, similar to shading, directly interfered with leaf photosynthesis by repressing photosystem II (PSII) efficiency within 10 minutes of treatment, suggesting that NAA and shading induced some of the same early responses due to reduced photosynthesis, which concurred with changes in hormone signaling pathways and triggered fruit abscission.