Sentence examples for pathways and target from inspiring English sources

Bioinformatics of KEGG pathway analysis suggested that 4 differential expression miRNAs (miR-143, miR-145, miR-2325c and miR-2361) involvedifferenterent pathways and target genes may regulate the fat deposition differently.

Even within a class of pathogens, the invader can take different endocytotic pathways and target different intracellular sites [16].

TLR4 interacts with adaptor molecules, interacting proteins, effectors, downstream pathways and target genes, which together constitute the TLR signaling pathway.

In addition, using chemical inhibitors for various signaling pathways and target specific siRNAs, we dissected the role of EGFR-MEK1/2 pathway in regulating CIP2A expression.

Our findings open the way to further research not only on the interaction of VCC with other proteins on the pathogen side, but also on its interactions and effects regarding host's innate immune system, developmental pathways, and target cells where main events leading to pathogenesis take place.

The complexity of wnt signaling likely stems from two sources: multiple pathways emanating from frizzled receptors in response to wnt binding, and modulation of those pathways and target gene responsiveness by context-dependent signals downstream of growth factor and matrix receptors.

Molecular pathways and targets in prostate cancer.

Here, we constructed a whole-brain, three-dimensional (3D) map showing the tract pathways and targeting locations of these four motor cortical outputs in mice.

This approach, called Nexxus, may lead to the identification of new signal transduction pathways and targets for drug design.

Cancer is the result of numerous defects in key regulatory proteins and pathways, and targeting them with anticancer agents is associated with severe systemic toxicity.

The impetus for development of cancer therapeutics from non-cancer drugs stems from the fact that different diseases share common molecular pathways and targets in the cell.