Sentence examples for pathways and multiple from inspiring English sources
The next generation sequencing approach provides important clues on the mutational landscape of genes involved in signaling pathways in particular JAK/STAT, Wnt/β-catenin, p53 pathways and multiple chromatin regulator genes that significantly promote hepatocarcinogenesis.
Accordingly, our gene profiling in early Fe deficiency strongly suggests that the induction of genes by Fe deficiency is not begun by a single pathway in the regulation network, but involves multiple pathways and multiple components of activators even in early Fe deficiency.
We studied 24 reports of SPINK1 N34S in CP (2,421 cases, 4,857 controls) using reported etiological factors as surrogates for pathways and multiple meta-analyses to determine the differential effects of SPINK1 N34S between alcoholic and non-alcoholic etiologies.
Through these inflammatory pathways, and multiple others, CD40 signaling has been linked to RA development.
Its diverse clinical characteristics illustrate the complexity of the disease, involving several dysregulated metabolic pathways and multiple genetic targets.
For the remaining probands, multiple homozygous mutations in genes in hearing-relevant pathways and multiple heterozygous deleterious mutations were present.
This situation necessitates the use of very high levels of therapeutic compounds in order to achieve both multi-pathway and multiple effector mechanism inhibition.
Actin cytoskeleton appears to be the master regulator of the Hippo-YAP/TAZ pathway, and multiple extracellular signals are integrated to the cytoskeleton reorganization to transduce the signals to the core of the Hippo kinases module.
Immunological investigations point to a contribution of responses outside the Th2 pathway and multiple potential but unproven control mechanisms.
The cycle could be completed early during the admission pathway, and multiple cycles within a single admission were seen.
A signaling pathway in which there is a potential role of E-cadherin is the wnt pathway and multiple lines of evidence show that this is an important growth and survival pathway in CLL [ 3- 6].
