Sentence examples for pathways act as from inspiring English sources

These three signaling pathways act as positive (Wg and Ras) and negative (N) signals during progenitor formation [10].

Activation of these pathways have been invoked as an important tumor suppressor barrier, because these pathways act as potent inhibitors of proliferation or propagation of damaged cells.

Innate immune effector signaling pathways act as important drivers of myofibroblast transdifferentiation by provoking fibrosis.

Proposed theories for comorbidity of bladder and bowel disease include mechanisms of cross-sensitization in which the neural pathways act as a conduit for smooth muscle dysfunction [ 29].

Also in the cytoplasm, the NMD, NSD, and NGD pathways act as mRNA quality control and are activated in response to mRNAs containing premature termination codons (PTCs), no stop codon, or secondary structures such as stem loops, respectively.

It is likely that the increased oxidative stress associated with acute hypoxia and the subsequent damage to membrane structures and proteins, while activating apoptotic pathways, act as stimuli for HSP72 induction during hypoxia [ 3, 42, 43].

Cyclin D1, a key regulator of the G1/S transition and PI3K/AKT and MAPK signaling pathways, acts as mitogenic sensor in G1 [32], [33], [33].

Cysteine provided to plants through sulfate assimilation pathways acts as a source of reduced S for the biosynthesis of a number of S-containing compounds, including GSH.

However, for several viruses, there is functional and mechanistic evidence that components of the autophagy pathway act as host factors in viral replicative cycles, viral dissemination, or both.

Stabilizing networks : These pathways act primarily as homeostatic controls of the production of ROS and other metabolites involved in the various metabolic programs which occur in the mitochondria.

Under hypoxic conditions, the HIF pathway acts as a key transcriptional regulator of tumor-induced angiogenesis33.