Sentence examples for pathway upstream from inspiring English sources

(a) Inhibitor acting on a signalling pathway upstream and downstream of a 'merger' node (black circle).

Suppression of Hippo pathway upstream regulators such as Wts leads to premature exit from quiescence and reactivation of NSCs (Ding et al., 2016).

Cloning, transgenic, and expressional analysis of Ghd7 showed that this locus corresponds to a CCT (CO, CO-like, and TIME of CAB1) domain protein and functions in the photoperiodic flowering pathway upstream of Ehd1 and Hd3a [81], implying an alteration of panicle size and grain number as a consequence of Ghd7 response to photoperiod.

These results suggest that pyrvinium likely targets the UPR pathway upstream of GRP78.

The cysteine-dependent redox switch can regulate ROS signaling pathway upstream of FOXO.

The molecular mechanism of activation and signaling pathway upstream of TGs has not yet been elucidated in ocular surface tissues.

For example, ZnT8 may participate in the insulin secretory pathway upstream of membrane depolarization; however, there are no data to support this speculation at present.

Any influence of gata3 on the IGF pathway upstream of PKB/Akt should be reflected in the activation of these kinases.

Recently, BH3-only death factors have emerged as key intermediates connecting multiple noxious signals to this "dual-core" apoptotic pathway upstream of the multidomain proteins [12], [13].

Gab2 may also act in a linear pathway upstream or downstream of signal transducer and activator of transcription-5 (STaT5), a major positive regulator of HSC function.

Modelling MAPK pathway upstream inputs and downstream response using basic Michaelis-Menton kinetics describes increasing non-linearity (Hill coefficient) of the downstream response with successive addition of intervening kinases [55].