He was playing the best, most energetically relentless club rugby of his life – be it in the Premiership or the Heineken Cup, he was the union code's physical embodiment of the Noel Coward dictum that "work is much more fun than fun" – but the steep pathway to England recognition seemed impassable.
Although the role of cholesterol in the genesis of atherosclerosis and CAD seems obvious today, the pathway to that recognition has been littered with obstacles.
For other illnesses where immune dysfunction or immune insult is suspected as a possible pathway to disease, recognition of likely immune involvement is even less apparent (e.g., neurobehavioral, neurodeficit, and fatigue disorders).
The abnormal presence and/or topology of LAMP in the content of phagolysosomes (as observed during L. amazonensis transfer events) could act as a danger associated molecular pattern (DAMPs), triggering IL-10 productitn; it could also activate signalling pathways related to recognition of apoptotic/necrotic bodies, leading to anti-inflammatory immune responses which involves IL-10 and TGF-β.
The technology implications of using CNTs-hydrogel are significant to many fields, from semiconductor device manufacturing to emerging areas of nanobiotechnology, nanofluidics, and chemistry, where the ability to mold structures with molecular dimensions might open up new pathways to molecular recognition, drug discovery, catalysis, and molecule specific chemobiosensing [ 83].
The process might involve a mechanism similar to that of Modulators of Immune Recognition, viral proteins involved in the immune recognition pathway, to which RPHM21 showed structural similarities.
The proven pathway to peace is mutual recognition and renunciation of violence.
Damage is recognized by RPA, XPA, and XPC, and the enzyme specificity is ensured by the kinetic proofreading function of TFIIH, which hydrolyzes ATP along several steps of the damage recognition pathway to discern damaged DNA.
Our data suggest that IME-2 is a negative regulator of a cell death pathway that functions in parallel to the VIB-1 HI pathway to specifically regulate nonself recognition and cell death when strains carry incompatible specificities at het loci.
Most mRNAs encoding transmembrane and secreted proteins are anchored on the ER by the signal recognition particle pathway to allow co-translational translocation of the signal peptide into the ER.
This model tries to transfer the knowledge learned from object recognition in the ventral pathway to localizing the target in the visual search task with zero-tuning.
