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As the N. crassa Δime-2 mutation restores extracellular protease production in a strain lacking all three NDT80 -like genes, IME-2 must regulate a parallel signaling pathway that does not exist in A. nidulans.
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Today, that doesn't exist anymore.
In Chile that doesn't exist.
Today that doesn't exist.
In civilian life, that doesn't exist".
Others want help that doesn't exist.
It also overestimates GO categories (i.e., it annotates many functions even for pathways, processes, or cellular components that do not exist in the test organism); thus, FDR is also somewhat overconservative globally.
The proposed method inserted six edges that did not exist in the true pathway.
They would then need to construct a new metabolic pathway, the chemical circuitry that a cell needs to do its job one that did not exist in the natural world.
They would then need to construct a new metabolic pathway, the chemical circuitry that a cell needs to do its job — one that did not exist in the natural world.
DOENITZ: No, that did not exist.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com