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The positive effect of the AKT pathway on the mTORC1 pathway summarizes AKT and PIM's inhibition of PRAS40, as well as AKT and SGK1's inhibition of TSC; both PRAS40 and TSC are inhibitors of mTORC1.
Each pathway summarizes abundance differences depicted as side-by-side heat maps that display the ratio of the individual cultivars average to the overall cultivars average abundance for each data point.
This pathway summarizes different cytokines and their receptors, and since several of these receptors are differentially expressed it makes sense that this pathway fulfills a central role in the network, by connecting to the different processes these receptors play a role in.
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Coexpression epistasis assays were able to specify where dSno might be acting in the Wg pathway (summarized schematically in Figure 8).
Many of the cyclic genes identified to date belong to the Notch signalling pathway (Summarized in Table 1).
Below we focus on the pathway summarized in Figure 3c, which includes both GDH and GS-GOGAT.
STN-DBS increased the effective connectivity of the direct pathway, summarized here as a net excitatory connection from the putamen to the thalamus.
Upon release of active homodimers from the DISC, caspase-8 cleaves and activates downstream substrates of the apoptotic pathway (summarized in Figure 2).
This pathway, summarized in Figure 11, involves a series of enzymes: E1 (ubiquitin-activating enzyme), E2 (ubiquitin-conjugating enzyme), and E3 (ubiquitin-protein ligase).
As mbtB is a mycobactin biosynthesis gene, the pathway summarizing the biosynthesis of mycobactin (Biosynthesis of siderophore group nonribosomal peptides) is one choice to look for the impact of this gene on metabolism and other genes involved in the pathway.
Thus, these studies identify a single molecular pathway (summarized in Fig 8) that enables suppression of tumour initiation by BLBC cells and that also renders established BLBC tumours responsive to treatment with µM concentrations of TMX.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com