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In the case of PHF6, the observed dominant association pathway started from a generic encounter complex with specific side chain contacts.
It is likely that the assembly of the pathway started with these two initial steps.
The slow progress in getting this pathway started may have been due to long-standing and deeply entrenched practices, as well as to certain stakeholders' resistance to change.
Comparative genomic analysis showed that gluconeogenesis is well conserved among wide-ranging species, suggesting that the metabolic pathway started expanding around pyruvate.
The core elements were: At the emergency room, when the diagnosis was clear, the care pathway started with an extensive nursing protocol.
A liver cholesterol biosynthetic pathway started with HMG-CoA reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonate [ 33], which is the first key chemical in the biosynthetic pathway leading to cholesterol as the final product.
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Hydroperoxide pathway starts with hydroperoxidation of polyunsaturated fatty acid, linoleic acid.
The cAMP signaling pathway starts the activation of sperm motility by phosphorylation of some proteins.
The preferred pathway starts with loss of native contacts between N-terminal -β33 N-terminal -β3with N-terminal -β3
ABA biosynthesis via terpenoid pathway starting from isopentenyl pyrophosphate (IPP) has been reviewed in rice (Ye et al. 2012).
Cyanobacteria and plants synthesize carotenoids via a poly-cis pathway starting with phytoene, a membrane-bound C40 hydrocarbon.
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