Sentence examples for pathway slow from inspiring English sources

These findings suggest that cholesterol ester accumulation in macrophages triggers autophagy and that accelerators of this pathway slow atherosclerosis.

Additional functional gene groups that were upregulated in mdx muscle after THI treatment were those related to the insulin pathway, slow twitch muscle, metabolism, sarcomeres and the WNT pathway, whereas inflammation-related genes were downregulated, compared with levels in untreated control mdx adductor muscles (Fig. 5C).

Inhibition of the ATR-Chk1 pathway slowed down both fork breakage and repair, suggesting that this pathway stimulates several steps of the lesion processing during DNA replication.

The defective R-LMC pathway sped up the LMC and probably AC output, mimicking extreme light adaptation, while the defective L2-R pathway slowed down the LMC output, mimicking dark adaptation.

But, coincidentally, inhibition of the TOR pathway slows down aging.

And inhibition of mTOR pathway slows down aging thus age-related diseases in varies species [ 22].

If genetic inhibition of the TOR pathway slows aging, then rapamycin, a drug that inhibits TOR, must slow aging too.

Genetic inhibition of the TOR pathway slows down aging in diverse organisms, including yeast, worms, flies and mice [ 29- 33].

Calorie restriction (CR), which deactivates the nutrient-sensing mTOR pathway, slows down aging and prevents age-related diseases such as type II diabetes.

On the other hand, interventions on metabolism such as calorie restriction or genetic manipulations of key metabolic signaling pathways such as the insulin and mTOR signaling pathways slow down the aging process and improve healthy aging.

In Drosophila, nutrient limitation or changes in nutrient-sensing pathways slow germ cell proliferation, reduce germline stem cell number, or both (Armstrong et al., 2014; Drummond-Barbosa and Spradling, 2001; Hsu et al., 2008; LaFever et al., 2010; McLeod et al., 2010; Roth et al., 2012; Sheng and Matunis, 2011).