Sentence examples for pathway settings from inspiring English sources

Based on the findings in the first set of analyses, the second class of simulations further explores the functional importance of the relevant recovery pathways and their relationships to details of the intracellular pathway settings, such as the relative magnitudes of different flux rates and balances between forward and reverse reactions.

However, the role of the Wnt pathway in such settings remains unclear.

Altogether, these vectors can probe and modulate the Wnt signaling pathway in experimental settings where persistence of the transgene or gene transfer cannot be accomplished by non-viral techniques.

The possibility remains that p53 status truly regulates Wnt pathway activity in settings of lower levels of Wnt signalling.

Accordingly, these data may indirectly support our findings and suggest that the TWEAK/Fn14 pathway increases inflammatory settings and thus further enhances cell motility in podocytes leading to proteinuria.

Exposure to YC-1 led to a significant alteration of the cell cycle pathway in both settings (Additional file 8: Figure S5B).

The importance of including all relevant stakeholders and the benefit of continuous and reflective learning was also demonstrated in a study about the development of a care pathway across different settings and independent disciplines [ 31].

Adopt an incremental and modular approach to development so that existing datasets can be utilised to provide relatively "quick wins", with the option to extend the pathway to new settings and service areas as more data become available over time.

The computational results also reveal that the optimal design of the three subunit recovery pathways depends on the intracellular settings of the pathway and that the response speeds of key reversible reactions within the pathway are of great importance.

While most studies suggest that inactivation of Kif3a reduces Hh signal transduction [45], [46], [47], [53], Kif3a may also activate Hh signaling pathways in some settings [68], as we observed in heterozygous Kif3a+/Δ mice.

The pathogen-specific transmission pathways and exposure settings identified can help inform prevention efforts.