Sentence examples for pathway requirements from inspiring English sources
Overall our results highlight key tissue-specific differences in transgene presentation pathway requirements of importance for the design of rAAV-based T cell-inducing vaccines.
Likewise, mTOR inhibition could also be tested in our temporal controlled Pten-deficient tumor model and this will allow the dissection of mTOR pathway requirements when Pten is lost in systemic organs.
Other secretion systems use complex multi-component protein assemblies that bypass the Sec pathway requirement and directly translocate proteins from the cytoplasm to the extracellular milieu.
Although little is known about the specific downstream components that link the transceptors to PKA in the FGM pathway, requirement of the Sch9 kinase for amino acid and ammonium activation in nitrogen-starved cells has been demonstrated (Crauwels et al., 1997).
To achieve site-specific biotinylation of proteins within the secretory pathway, two requirements must be fulfilled: i) the protein of interest tagged with the appropriate BAP sequence, and ii) the biotin protein ligase expressed within the secretory compartment, i.e. the endoplasmic reticulum (ER).
We also hypothesize an independent regulation of the MAPK and cAMP signaling pathways and an up-regulation of the TOR signaling pathway as necessary requirements.
Cowling V, Downward J. Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain.
In this work, we report the development of alternatives to antibiotics as tools for host-pathogen research during Yersinia pestis infections focusing on the diaminopimelic acid (DAP) pathway, a requirement for cell wall synthesis in eubacteria.
Such strategy provides the possibility to have independent control on the associated reactions in response to pathway-specific requirements.
Although BCL-2-associated BCL-2-associated BCL-2-associated Xt killer (BAK) are critical regulators of the mitochondrial aproteins pathway, their requirement has not BAXn robustly estandished in relation to cisplatin.
As will be discussed in detail below, the traditional regulatory pathway's requirement for large phase III programs is a challenge if we wish to have new agents developed in advance of widespread resistance.
