Exact(15)
The research related to the multitude of circulating and urinary biomarkers of inflammation and other novel and emerging biological pathways in MESA is summarized by domain, or pathway, represented by the biomarker.
Several studies support the hypothesis of cortical excitability as a possible mechanism underlying their pathology, such as Na + −K + ATPase pump impairment, converging on a common final pathway represented by neuronal membrane hyperexcitability, could manifest as either epilepsy or headache/migraine [9].
Corrections were not made for multiple testing among variants since there is clear biological evidence that each pathway represented by the candidate SNPs in this study is involved in the regulation of t-PA and PAI-1 expression either directly or indirectly meaning that the universal null hypothesis of association by random chance does not apply [19].
The most significant pathway, represented by these genes was "Chemotaxis/CXCR4 signaling pathway" (p = 2 × 10-6).
Secondly, inhibition of the MAPK pathway, represented by ERK1/2, was reached with erlotinib alone in SKBR3 and HCC1954.
Interestingly, the cell cycle pathway represented by 63 genes on the microarray did not significantly change at any of the three time points examined.
Similar(45)
One step further, we compared the pathways represented by different published prognostic gene signatures with the over-represented pathways associated with metastatic capability.
Crustaceans bear multiple parallel chemosensory pathways represented by different populations of unimodal chemosensory and bimodal chemo- and mechanosensory sensilla on the mouthparts, the walking limbs and primarily on their two pairs of antennae.
Only GO terms and KEGG pathways represented by 50 or more microarray cDNAs were included.
GO pathways represented by genes up-regulated by IFN-β+APAP treatment were identical to the IFN-treatment group.
Furthermore, Pathway Express (http://vortex.cs.wayne.edu/ontoexpress) was used to identify relevant pathways represented by the differentially regulated gene set.
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