Sentence examples for pathway progression from inspiring English sources

It has been discussed whether Cyclops, in addition to its role in mycorrhization and infection thread formation, is also involved in nodule organogenic pathway progression [7], [15].

These individual modular interaction sites, which allow protein exchanges and pathway progression, also provide possible targets for new therapeutic strategies.

There are many novel insights that come directly from these structures and associated analyses, such as the ATP-bound MutS conformation and the rearrangement of the connector domain that creates a second interface with MutL to regulate pathway progression.

Such conformational switching in Rad50 controls pathway progression and the choice between DNA end joining and excision, which may have parallels to these new MutS results or not (Deshpande RA et al., ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. EMBO J. 2014 33, 482-500).

Furthermore, in a large pooled analysis examining the effect of timing of exposure, smoking cessation (compared to continued smoking) conferred a markedly reduced risk of cancers in right colon, but not in the left colon [ 4], supporting the idea that smoking may be a key in promoting late pathway progression to serrated carcinomas.

These therapies all have level A evidence for efficacy and a clear pathway of progression if initial therapies fail is provided.

Low grade ductal carcinoma in situ and in situ lobular carcinoma are now believed to belong to the same low-grade pathway of progression to invasive carcinoma [ 31].

Mohammed et al. reported that gefitinib blocks EGFR signaling pathway in progression of pancreatic intraepithelial neoplasms (PanINs) to PDAC in conditional LSL-KrasG12D/+ transgenic mice model [ 36].

The pathway of progression of fibrosis in RT kidney leading to RT loss comprises time-dependent series of pathological insults causing histological changes.

The effect could only last for 3 6 months as the melanoma cells develop resistance to drug-induced apoptosis and aberrant survival pathways during progression [15].

From re-writing parental leave policies, to establishing mentorship programs and defining clear pathways for progression, as business leaders, we believe the best way to accelerate the movement for gender equality is to start at home, transforming our own companies and industries.