Sentence examples for pathway profiles from inspiring English sources

In addition, we were able to identify common gene pathway profiles associated with the presence of these mutations.

Using a human model incorporating varying infection severity, we found important differences in pathway profiles of circulating leukocytes between asymptomatic, mild and severe influenza infection.

Characterizing and tracking changes in intracellular pathway profiles in cell subpopulations both at baseline and under therapeutic pressure will likely have important clinical applications, potentially informing the selection of beneficial targeted agents, used either alone or in combination with chemotherapy.

We then evaluated the performance of these metrics (sBEF or enrichment score), as expressed in the ability of assessing similarity according to the expectation that biologically similar experiments should show identical or similar pathway profiles (defined as collections of PEFs, sBEFs or enrichment scores for the pathways used for testing).

When taken together, trends for apoptosis, Jak/Stat and PI3K pathway activities (Figures 3, 4, and 5) and clinical outcomes (Table S1) suggest that there are limited number of pathway profiles associated with CR patients, whereas in NR patients many different pathway mechanisms may have evolved for the leukemia to be refractory to chemotherapy.

We then calculated the reproducibility of pathway profiles in each data set against the reference pathway profiles for each subtype.

(i) Titration inhibition of the p38 pathway profile by 1 and 2 as measured by HSP27 phosphorylation.

Enzyme and KEGG pathway profiling predicts that kinases, esterases, and hydrolases may contribute to venom activity in this unique wasp.

The minimum energy pathway profile shows that the phosphodiester bond cleavage step of the reaction is kinetically controlled and not thermodynamically because of a lack of any energy barrier above the accuracy of the energy profile calculation.

Additionally, gene pathway profiling was performed with candidate genes using the Ingenuity Pathway Analysis software.

The plasmids pTA-Control and pTA-GAS are part of the Mercury Pathway Profiling Luciferase Systems 5; catalogue number K2057-1 (lot# 2060828) (Clontech, Mountain View, USA).