Sentence examples for pathway of vulnerability from inspiring English sources
Here, we revisit the question of DISC1 function through network analysis and identify multiple links to huntingtin (HTT), suggesting an overlapping pathway of vulnerability between DISC1-related psychiatric disorders and Huntington's disease, a neurodegenerative disorder characterized by a deterioration in motor, cognitive, and emotional function.
These reveal pathways of vulnerability and provide targets for rational drug design.
In summary, we have isolated a novel CRI-G1-RS subclone of the CRI-G1 insulinoma cell line that shows increased expression of β cell differentiation markers, reconstitution of GSIS, decreased activity of ARE/Keap1/Nrf2 pathway, and increased vulnerability to mitochondrial dysfunction and oxidative stress compared to the parental CRI-G1-RR cells.
Combination prevention combines behavioral, biomedical, and structural interventions to address both the immediate risks and underlying causes of vulnerability to HIV infection, as well as the pathways that link them [ 41].
Assessment of vulnerability and desirable mode of enzyme inhibition was illustrated using CoA biosynthetic pathway whereas change in branched chain amino acid levels illustrated its application in finding suitable metabolite markers following target inhibition.
The current findings might be further interpreted to suggest that defects in the P4-induced cholesterol biosynthesis pathway might increase vulnerability of OSE cells to inflammatory or physical damage and increase the risk of neoplastic transformation.
Smothers looked for a moment of vulnerability.
Still, they felt a measure of vulnerability.
Still, the Bruins hinted of vulnerability.
With that, the moment of vulnerability passed.
