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Advanced refolding strategies by pulsed refolding and temperature leap, favoring the native pathway of specific model proteins were also implemented.
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Common pathways of specific miRs were identified using the DIANA-microT 3.0 target prediction program (http://diana.cslab.ece.ntua.gr/microT/).ntua.gr/microT/
Functional and Canonical Pathway analyses of specific gene datasets were generated through the use of Ingenuity Pathway Analysis (Ingenuity Systems®, http://www.ingenuity.com).com
In 14 out of the 16 datasets with at least one enriched pathway, the number of specific pathways exceeds the number of common pathways.
Several pathways indicative of specific lymphocyte subsets are differentially expressed by CMCs.
This methodology has been used to develop two different models of lung adenocarcinoma to analyze activation of pathways downstream of specific mutations and to assess the potential of therapeutic targeting strategies [ 112, 113].
Antitumor agents such as cisplatin can activate the pathway, but the role of specific pathway components in cell sensitivity/response to the drug is not known.
However, regulation of genes involved in carotenoid biosynthetic pathway and accumulation of specific carotenoid in chromoplasts are not well understood.
One signalling pathway that is of specific interest in this context is the stress hormone system [ 28].
One synthetic biology approach fine-tunes the enzymatic pathways of a specific product, enabling the transfer of optimized systems to another chassis.
It suggests that α5β1/GSK3β and α4β1/Pyk2-dependent pro-survival pathways could cooperate through the activation of specific pathways of resistance to extrinsic and intrinsic pro-apoptotic pathways.
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