Sentence examples for pathway of selection from inspiring English sources
The graph in Figure 4A is based on a spreadsheet simulation that uses the measured parameters to show that colonies following this pathway of selection can appear well within the time of the experiment, using standard unselected mutation rates (see File S1).
Finally, an alternative selection strategy considering only 2 pathways of selection for genotyped male calves and for cow dams was evaluated.
For most schemes it was assumed that the reliability of genomic breeding values (GEBV) was 0.6 across 4 pathways of selection.
At the level of pathways, signatures of selection can be traced through the selection acting on individual genes constituting the pathway.
This observation is consistent with the results of other studies linking fluoroquinolone use to resistance in these pathogens (4– 11), although the pathways for selection of resistance differ between the 2 pathogens.
Second, since different genes in the thyroid hormone pathway show signals of selection in Mbuti vs. Biaka Pygmies, this would suggest that short stature arose independently in the ancestors of Mbuti and Biaka Pygmies, and not in a common ancestral population.
Clearly, the present model also allows for pathways of negative selection leading to the elimination of spurious binding sites in regulatory or non-regulatory DNA where the binding has an adverse fitness effect.
Moreover, the identification of candidate pathways for signatures of selection is a significant step towards understanding accession diversification and their adaptation to the environment.
We thus aim to continue comprehensive benchmarking of biological pathways to facilitate evidence-based pathway selection of biomedical researchers.
It is generally assumed however that clustering of genes in biosynthetic pathways is the result of selection against toxic intermediates produced by incomplete pathways [ 49].
As shown in previous sections, the procedure of pathway selection by retrosynthesis is a complex task that implies the adoption of several design decisions, some of them on a case-by-case basis.
