Sentence examples for pathway of nucleotides from inspiring English sources

Three routes exist for the maintenance of proper intracellular nucleotide pools: a) de novo biosynthesis, which requires folate cofactors and is restricted to selected cell types; b) the salvage pathway, which utilizes intermediates from the degradation pathway of nucleotides; and c) influx of nucleosides from the extracellular milieu.

We found that M. gallisepticum has the full pathway of nucleotide excision repair and recombination of DNA.

Mycophenolic acid (MPA) is a selective inhibitor of inosine monophosphate dehydrogenase which leads to inhibition of the de novo pathway of nucleotide synthesis.

These enzymes are known to be involved in the biosynthesis pathway of nucleotide activated glycerol-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides [ 16].

The ability of the folate-independent salvage pathway of nucleotide biosynthesis to modulate metformin reduced breast cancer cell viability was monitored by using a standard colorimetric MTT (3-4, 5-dimethylthiazol-2-yl-2, 5-diphenyl-tetrazolium breductioneduction assay.

Equilibrative nucleoside transporters (ENTs), which facilitate cross-membrane transport of nucleosides and nucleoside-derived drugs, play an important role in the salvage pathways of nucleotide synthesis, cancer chemotherapy, and treatment for virus infections.

We have established inducible UMP/CMP kinase cell lines as cell models in an attempt to understand the active pathways of nucleotide metabolism.

This protein participates in the transcription-coupled repair (TCR) sub-pathway of nucleotide excision repair (NER).

RNA silencing refers collectively to diverse RNA-mediated pathways of nucleotide-sequence-specific inhibition of gene expression.

Of particular interest are the genes most upregulated by ArcA in aerobiosis with H2O2 in the pathways of nucleotide and glutathione metabolism, coding for the alternative ribonucleotide reductase (nrdEF) and glutathione reductase (gor).

The DNA-damage response (DDR) network, including complementary DNA-repair pathways of nucleotide-excision repair (NER), base-excision repair (BER), mismatch repair (MMR), homologous recombination (HR), non-homologous-end-joining and inter-strand-crosslink repair (ICLR), counteracts genomic erosion.