Sentence examples for pathway of major from inspiring English sources

This direct link provides a hereto novel mechanism for extracellular control of ubiquitin ligase activity that is used for the modulation of Wnt signalling, a pathway of major importance in embryogenesis, stem cell biology and cancer.

Indeed, the evidence for both mechanisms suggests that CO may be involved in a neural signaling pathway "of major importance," adds Paul Greengard of Rockefeller University in New York City.

Although DA concentration is the direct cause of such diseases, since the biosynthetic pathway of major catecholamine neurotransmitters has been well-understood (Figure 1), the concentration measurements of these individual neurotransmitters (L-Tyrosine, L-DOPA and DA) could provide meaningful insights on the failure mechanisms along the pathway.

These enzymes play important roles in triterpene saponin biosynthesis, particularly for DS, which is the first committed enzyme in the biosynthetic pathway of major triterpene saponins.

Hence, mechanical stress result in different proportions of vessel elements as biosynthetic pathway of major woody cell wall components can be switched on and off.

In particular, the transcript encoding dammarenediol synthase (DS), which is the first committed enzyme in the biosynthetic pathway of major triterpene saponins, is highly expressed in the root of four-year-old P. notoginseng.

In our case study, these focus scenarios reflect the potential development pathways of major national-level drivers for ecosystem service management in Swiss mountain regions.

In the second section we revise new therapeutic strategies based on new drug families that target key molecular pathways of major relevance in this malignancy.

Specific investigations to elucidate the exposure pathways of major environmental exposure need to be conducted, and the KorEHS-C should cover as many potential environmental hazards as possible.

However, it is not clear what are linkages and pathways of major climate change drivers of temperature, snowpack, and precipitation with water, energy, food, and related key ecosystem processes for these habitat loss and species extinctions.

This study discusses the formation pathways of major secondary aerosol components.