Sentence examples for pathway of dna from inspiring English sources

Virtually every pathway of DNA repair requires DNA synthesis and involves the PCNA molecule which can recruit the H3.1/2 chaperone CAF1 for deposition of H3.1/2 in the absence of replication (e.g., according to the 'access-repair-restore' model (Smerdon, 1991)).

Ku70 and Ku80 make up the Ku heterodimer, which binds to the ends of double-stranded DNA breaks and is required for the non-homologous end joining (NHEJ) pathway of DNA repair [ 34].

In most ascomycete fungi, disruption of the NHEJ pathway of DNA repair leads to elevated gene targeting efficiency because the HR pathway remains the only functional DNA break repair mechanism resulting in increased frequency of HR between the genome and foreign DNA (Ninomiya et al., 2004; Kershaw and Talbot, 2009).

NER is an essential pathway of DNA repair and the only known mechanism in mammalian cells for the removal of bulky, helix-distorting DNA adducts produced by platinum agents (Park et al, 2001).

A combination of a temperature spike and electron/hole interactions may be a dominant pathway of DNA damage.

Targeting nucleic acids using small molecules routinely uses the end products in the conversion pathway of "DNA to RNA, RNA to protein".

The aim of the study was to verify the hypothesis that the metastasizing behavior of CM could be correlated with the alteration of more than a single epigenetic pathway of DNA-repair and cell proliferation control, and to establish the possible role of CAF-1/p60 as a new valuable predictor of prognosis for skin melanoma patients.

It is composed of the activity scores of six pathways: Trka Pathway, DNA Damage pathway, Ceramide Pathway, Telomerase Pathway, CD40L Pathway and Calcineurin Pathway.

Genome engineering with targetable nucleases depends on cellular pathways of DNA repair after target cleavage.

This enzyme catalyses hydrolysis and transfer of nucleotide-containing substrates in metabolic pathways of DNA, RNA and carbohydrates.

Non-Homologous End Joining (NHEJ) is one of the two major pathways of DNA Double Strand Breaks (DSBs) repair.